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Chemical burns can continue damaging tissue until the causative agent is completely neutralized or removed
so it should be addressed separately
Repeated freeze-thaw cycles: Each cycle risks partial aggregation and loss of activity
doi: 10.1007/s00125-018-4803-z 23 DeFronzoR
Some prefer bi-weekly treatments during high-stress periods, while others find quarterly sessions sufficient for seasonal support
The synthetic variant may have superior hair-specific activity based on community reports, though controlled comparisons remain limited
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